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Showing posts from May, 2022

The Tale of a Rubbery White Clot: Poorly Differentiated Spindle Cell Sarcoma Presenting As Superior Vena Cava Syndrome - Cureus

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Sarcoma is an uncommon neoplasm of mesenchymal origin (1). The presentation is usually vague. It may present as a mass in the thigh or retroperitoneum, with resultant pain or paresthesia of the affected area. The diagnosis is very challenging due to its indistinct presentation. The prognosis remains poor due to delays in diagnosis and few available therapeutic options. We herein report the first case of superior vena cava (SVC) syndrome caused by spindle cell sarcoma. Introduction Sarcoma is a heterogeneous collection of malignant tumors of mesenchymal origin that is extremely rare. It accounts for less than 1% of all adult cancers [1]. The cause of most sarcomas is unknown. Genetic predispositions [2], such as Li-Fraumani syndrome, neurofibromatosis type 1, and retinoblastoma; radiation therapy or chemotherapy exposure; carcinogen exposure; chronic irritation, lymphedema, human immunodeficiency virus, and human herpesvirus 8, are some of the known correlati

Lupus and gastroenteritis: Link, symptoms, and treatment - Medical News Today

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Gastroenteritis refers to inflammation of the stomach and intestines that leads to symptoms such as diarrhea and vomiting. When lupus affects the intestines, health experts call this lupus enteritis. Lupus does not cause gastroenteritis, but it can cause similar symptoms. Lupus is an autoimmune condition leading to inflammation that can affect several parts of the body, including the gastrointestinal (GI) system. Both lupus and treatments for the condition can interact with the GI system. The symptoms are nonspecific and can include nausea and abdominal pain. Lupus can lead to widespread inflammation, including inflammation of the blood vessels in the intestine. Health experts refer to this as lupus enteritis. However, lupus enteritis is a rare condition, and it is more likely that symptoms will occur due to an infection, medication side effects, lupus itself, or another underlying condition. This article reviews how lupus and gastroenteritis relate, including their symptoms and treatm

Black men die of prostate cancer at double the rate of all other races - Amsterdam News

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Benjamin J. Lambert IV, a member of one of the most prominent Black families in Virginia's public service history, lost his battle to prostate cancer on Monday, June 3, 2019. He was only 52. His father, Virginia Senator Benjamin J. Lambert III, his grandfather, and four uncles also all died of prostate cancer, according to Lambert family members. The Lamberts are just seven examples of the thousands of Black men per year – from every socio-economic walk of life and every part of the U. S. – who are disparately diagnosed with prostate cancer. Not only is the rate of prostate cancer among Black men higher than Whites, but the chances of Black men dying from it are more than double that of White men and men of other races, according to the National Cancer Institute. But doctors and medical administrators across the nation believe these grossly disparate numbers can be minimized or at least equalized by one form of cancer therapy that top-level cancer doctors and resear

New biomarker could improve ovarian cancer diagnosis in younger women - Clinical Trials Arena

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Ovarian cancer is the eighth most common cancer in women worldwide, and the leading cause of mortality from gynaecological malignancy. As its symptoms—abdominal bloating, feeling full quickly after eating, and back pain—are not unique to ovarian cancer, it is often difficult to diagnose at an early stage. Women diagnosed with Stage I ovarian cancer are more than 90% likely to be alive five years after their diagnosis, but this falls to 13% for those diagnosed with Stage IV disease. A UK study published at the end of last month, however, found that a new blood biomarker improved the detection of ovarian cancer, results that could one day lead to the development of a blood test to diagnose the cancer more quickly and accurately. If such a test becomes common practice for diagnosing ovarian cancer, GlobalData epidemiologists expect incident cases in the UK to increase. The study, conducted by Barr and colleagues and published in Cancers, assessed the diagnostic accuracy of the new

Surgical innovation uses electrical pulses to beat prostate cancer, technique called ‘game-changer’ - OregonLive

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A unique surgical technique, commonly called NanoKnife, uses electricity to zap hard-to-reach prostate-cancer tumors and promises fewer side effects. Prostate cancer is the most common cancer for men, other than skin cancers, yet it can be difficult to catch early. Treatments for it typically are blunt, including removal of the prostate, and can cause incontinence and impotence. The NanoKnife procedure, known as irreversible electroporation, usually takes only 45 minutes to an hour, and doctors have called it "amazingly simple and quick" and a "game-changer." It targets the tumor specifically and mostly leaves unscathed the rest of the prostate, including the nerves needed for bladder control and erectile function. "It's an amazing treatment, so quick, and it means we can reach tumors that are beyond where the knife can reach," British surgeon and University College London professor Dr. Mark Emberton told The Daily Telegraph. The procedure is still goi

Stage 4 ovarian cancer: Symptoms, treatment, and survival - Medical News Today

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Doctors use staging of ovarian cancer to decide which treatment options are the most suitable for a patient. In stage 4, the cancer has spread beyond the ovaries to distant areas of the body. Treatment options available for people with stage 4 ovarian cancer include surgery, chemotherapy, targeted therapies, immunotherapy, and palliative care. This article looks at what stage 4 ovarian cancer is and whether it is terminal, as well as symptoms and treatment. It also looks at things to consider, survival rate, and where to find support. If ovarian cancer is stage 4, it means the cancer has spread to distant parts of the body, such as the lungs or liver. The main treatment for this stage is surgery and chemotherapy. The stage of cancer describes how much the cancer has grown. A doctor may be able to diagnose and determine information about the cancer using tests and scans, but they may not be able to tell the exact stage until they perform surgery. Doctors stage ovarian cancer on a scale

Top Prostate Cancer Specialists | Prostate Doctors - RWJBarnabas Health

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From revolutionary screening and diagnostic technologies to groundbreaking therapies – our prostate cancer team delivers care that is continually focused on your prostate health and overall wellness. Prostate Doctors Our experienced prostate doctors thoroughly evaluate your risk factors and recommend screenings to monitor your prostate health. Urologists are surgeons who treat urinary system and male reproductive system diseases, including the prostate. Radiation oncologists are doctors who treat prostate cancer with radiation therapy. Medical oncologists are doctors who treat prostate cancer with chemotherapy, hormone therapy, and immunotherapy. Their comprehensive approach ensures an accurate diagnosis and access to the best treatment. Their unwavering attention to patient care, comfort, and convenience allows you to focus on your health. Top Prostate Cancer Physicians Men with prostate cancer may have sur

Understanding Unicentric and Multicentric Castleman Disease - Healthline

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Castleman disease is a rare condition that affects your body's lymph nodes, causing one or more of them to enlarge. Castleman can become life threatening if not treated, causing infection and organ damage. Lymph nodes are small glands located throughout your body, in the armpits, neck, groin, and elsewhere. Your lymph nodes filter a clear fluid called lymph for your body's lymphatic system. They also store white blood cells, which protect your body against infections by destroying invading bacteria and viruses. Some people with Castleman disease have no symptoms at all, while other people have symptoms that are similar to the flu. The exact cause of Castleman disease isn't known, but having HIV is the largest risk factor for developing the condition. Treatment for Castleman depends on how many lymph nodes are affected, and where. In this article, we'll overview the types of this disease, possible symptoms, and what treatments are currently available. There are two types

Preventing skin cancer: Advice for before, and after, sun damage occurs - Medical University of South Carolina

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It's estimated that 20% of the U.S. population will develop skin cancer at least once in their lifetimes. What if there were a way to prevent certain skin cancers even after sun damage had occurred? Specialists at MUSC Hollings Cancer Center want to educate patients about the options available to them. Joni Mazza, M.D., an MUSC Health dermatologist and skin cancer specialist, said catching skin cancers early, or before they form, is important. "We are seeing more and more people being diagnosed with skin cancer at a young age," she said. "We don't know if that is because of tanning bed use or increased exposure to sunlight, but it is definitely a concern." The best ways to prevent skin cancer are to use the correct sunscreen, wear protective layers like a hat and to limit your exposure to sunlight. Living in the Lowcountry, Mazza understands outdoor activities are a way of life. Even after sun damage has occurred, she said there are nonsurgical

The Cost of Treating Prostate Cancer - Healthline

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About 7 percent of prostate cancer cases are metastatic. This means the cancer has spread from the prostate into other parts of the body. Prostate cancer usually metastasizes to bones. Treatment for any type of cancer can be financially overwhelming. Treating advanced cancer piles on the expenses at a time when your primary concern is comfort and recovery, whether it is your own or that of your loved one. Here, we'll give you some tips on managing treatment decisions for metastatic prostate cancer and what you can expect it to cost. Once prostate cancer has metastasized, treatment focuses on slowing the cancer's spread, controlling symptoms, and treating pain and discomfort associated with bone metastasis. According to the American Cancer Society (ACS) , treatments for metastatic prostate cancer include: androgen deprivation (hormone) therapy surgery radiation observation clinical trials using experimental treatments treatment for the pain of bone metastases immunotherapy chem

Cramps but no period: 9 reasons why you may feel pelvic pain - Insider

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Cramps but no period could be caused by normal ovulation pain or an ovarian cyst. If you suspect you may be pregnant, abdominal cramps could also be caused by an ectopic pregnancy, a miscarriage, or pregnancy itself. You may also feel abdominal cramping if you have chronic conditions like endometriosis or inflammatory bowel disease (IBD). Many of us have felt the uncomfortable lower-belly cramps that can come with your period. But cramps can show up outside of your period, too.  There are many conditions that can trigger abdominal cramps – and while many are normal, some may be dangerous and could require medical attention.  Here are nine reasons you may have cramps while not on your period, and some tips for how to tell what is causing your cramps.

Prostate Cancer: Janssen's Commitment to Patients Begins with Science - FiercePharma

[unable to retrieve full-text content] Prostate Cancer: Janssen's Commitment to Patients Begins with Science    FiercePharma

Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: A Rare Case - Cureus

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Primary salivary gland malignancies (SGMs) account for only 5% of all head and neck cancers, with the World Health Organization (WHO) describing 11 benign and 22 malignant subtypes of salivary gland tumors [1]. Carcinoma ex pleomorphic adenoma (CXPA) constitutes about 12% of all SGMs, with the majority of cases arising from the parotid gland (67%) [2]. Histopathologically, poorly differentiated adenocarcinoma and undifferentiated carcinoma are the most frequently encountered malignant components of CXPA with squamous cell carcinoma (SCC) being a rare finding [3,4]. Metastatic SGMs are an uncommon finding with only 20% of parotid gland malignancies showing metastatic potential [1]. According to Ali et al., lungs account for 49%, bones for 40%, and the brain for 7% of the total metastasis reported in a study. The study also suggested a distant recurrence percentage of 20% for CXPA [5]. "Occasional case reports exist of adenoid cystic carcinoma metastasizing to the pleural fluid, a