Prostate Cancer

[unable to retrieve full-text content] ‘If you are shy you will suffer’: men and prostate cancer    South China Morning Post https://ift.tt/2XRcfCw

Although one in nine men will receive a prostate cancer diagnosis in his lifetime, cutting-edge research has allowed more men to live longer or even be cured. Statistics show that one in nine men will receive a prostate cancer diagnosis during his lifetime, making it the most common cancer among men after skin cancer. But thanks to the work being done at institutions like City of Hope Comprehensive Cancer Center in California, more men are being cured each year, and those who aren’t cured are living longer. One such program that sheds light on this cause is City of Hope’s NoShaver November. The month-long fundraising and awareness campaign urges participants to forego shaving to start a conversation, encourage testing and raise critical funds to continue leading-edge prostate cancer research and promising new therapies conducted at City of Hope.  CURE ® recently spoke with Dr.  Tanya Dorff , a medical oncologist at City of Hope who specializes in prostate cancer, about the...

Prostate cancer incidence in older adolescent and young adult men has increased in most countries, but the cause for the rise is uncertain, according to a new study published online September 25 in the journal Cancer . "Men as young as 17 years are experiencing an increasing incidence of carcinoma of the prostate in much of the world," write an international team of authors, led by Archie Bleyer, MD, Oregon Health and Science University's Knight Cancer Institute in Portland. They report that the incidence of prostate cancer has increased in all groups between ages 15 and 40 years and increased globally at a steady rate averaging 2% per year since 1990 ( P < .01). However, prostate cancer is rare in young men, with incidence rates not rising above about 0.2 cases per 100,000 men until age 35 and being even lower at younger ages, per US data from the last two decades; notably, the rate spikes dramatically between ages 35 and 39, approaching 1.8 cases. However, at...

Sometimes after finishing prostate cancer treatment, men get an unwelcome surprise: their prostate-specific antigen (PSA) levels creep higher, suggesting tumors too small to be seen lurk somewhere in the body. This leads to several options. Doctors can continue to monitor a man’s condition with imaging scans. Or, given the anxiety associated with rising PSA, they might try to lower the levels with chemically “castrating” drugs that inhibit testosterone, a hormone that makes prostate tumors grow faster. Following that treatment, called androgen deprivation therapy (ADT), PSA generally declines and may become undetectable. But what if PSA climbs further despite ADT’s inhibiting effects on testosterone? This condition is called nonmetastatic, castration-resistant prostate cancer (nmCRPC). It’s called “nonmetastatic” because cancer hasn’t spread in a way that’s detectable with imaging technology. And it’s called “castration-resistant” because PSA isn’t responding to the chemically castrat...

Prostate cancer affects around one in eight men in the UK, but tends to be more common in men over the age of 65. Because there’s currently no cure for cancer, understanding what could potentially cause it can help prevent it. Doctors don’t yet known the exact reasons why some men develop prostate cancer, but a number of risk factors have been associated with the disease. Bupa explains: “Prostate cancer can run in families. Certain genes, such as one called BRCA2, can put people at higher risk. “So, if you have a close relative with prostate cancer, such as a brother or father, you’re more likely to develop it. “Men who eat a lot of high-fat foods may be more likely to develop prostate cancer too. READ MORE:  How to live longer: Best diet to increase life expectancy - how many calories to eat “You’re also more likely to develop prostate cancer if you’re black or over 50.” Recent studies have suggested links between sleep and prostate cancer risk, with one study asso...

Immuno-oncology therapies like checkpoint-inhibiting drugs have been largely ineffective in prostate cancer. Researchers at the University of Texas MD Anderson Cancer Center want to change that—and they believe they’ve found a drug combination strategy that could work. The challenge in treating prostate cancer is that when the tumors spread to bone, they destroy tissue, and in so doing they block the development of immune-boosting T cells that are critical to the success of checkpoint inhibitors. The MD Anderson team scrutinized that process in the hopes of finding a therapy that would prevent it. They discovered that when tumors destroy bone, massive amounts of a protein called transformational growth factor-beta (TFG-beta) are produced. That prevents helper T cells from transforming into the Th1 CD4 effector cells that would normally prompt the immune system to recognize and attack cancer in response to treatment with checkpoint inhibitors. Combining an anti-TGF-beta drug with a c...

News Life goes on but its quality is often diminished, according to a new study. A recent study has found many men's quality of life is diminished after experiencing prostate cancer. According to a new 10-year study , a significant number of Australian men affected by prostate cancer have lower life satisfaction and experience long-term impairments to quality of life as a result of the disease.   The study, the first of its kind to track men for a decade following a prostate cancer diagnosis, has prompted researchers to call for urgent action by health providers and policy makers.   Associate Professor Nicholas Ralph, Cancer Council Queensland and University of Southern Queensland researcher, has led these calls. He said more needs to be done to support the more than 200,000 Australian prostate cancer survivors.   ‘Although men with prostate cancer are living longer, they are not necessarily living well, with symptom burden increasing and quality of life ...

Prostate cancer can wreak havoc on men’s health. This is why it is important for men to identify the symptoms of this deadly disease. There are certain signs in your pee that will denote the presence of this deadly disease. The moment that you notice these signs make sure that you bring it to the attention of your general practitioner right away. The Macmillan Cancer Support pointed out certain signs in your pee. It explained that since prostate cancer would often press on the urethra, the signs often exhibit themselves on the way that you pee. Some of the signs that you need to watch out for include the following: Straining while peeing. When you pee and you find it difficult to do so, then there is a possibility that you are exhibiting a symptom of prostate cancer. Urgency whenever the need to pee is felt Finding blood in the urine. Frequent nighttime urges to pee. Retaining the feeling that the bladder has not emptied even after peeing. Whenever you observe any of the abov...

[unable to retrieve full-text content] Game Changing Treatments for Prostate Cancer    Jewish Chronicle https://ift.tt/2Ojr8cF

NEW HAVEN, Conn. (WTNH) – News 8 is on call for you. November is Men’s Health Awareness Month. Experts say men worry a lot about prostate cancer . Over two million men in the United States live with prostate cancer, and about 180,000 are diagnosed yearly. “A big change happened when we started screening about 20 years, 25 years ago. Most prostate cancers we find today are very small, they’re contained and highly curable,” says Dr. Michael Leapman. Dr. Leapman specializes in prostate cancer at Yale Cancer Center. Some common questions from patients: Is it genetic? He says, “It’s a good thing to pay attention to your family history. We hear a lot about the BRCA mutations for breast cancer and ovarian cancer in women but men who have a BRCA mutation are at greater risk for developing prostate cancer.” Is it something I did? “The answer is no,” says Dr. Leapman, “It’s not something that anyone did. It is completely out of someone’s control. There’s a lot of interest in diet, lifes...

MGN Online Movember – It’s a fun take on a very serious issue for men 55 years and older. On the heels of breast cancer awareness month, men are encouraged grow their beards and mustaches during the month of November, affectionately referred to as “Movember,” as a reminder to stay vigilant against prostate cancer. Affecting the prostate – a part of the male reproductive system located just below the bladder – prostate cancer can be a concern for all men, but the most common risk factor for developing the disease is age. According to the U.S. Centers for Disease Control and Prevention (CDC), approximately 13 out of 100 American men will develop prostate cancer during their lifetime. Because men often ignore signs and symptoms of the disease, nearly two-thirds of all men who develop the disease will die from it. Symptoms of prostate cancer include difficulty and or frequent urination, and pain in the backs, hips, or pelvis that does not go away. As with most other types of cance...

Prostate cancer is cancer that occurs in the prostate — a small walnut-shaped gland in men, and symptoms of prostate cancer do not usually appear until the prostate is large enough to affect the tube that carries urine from the bladder out of the penis (urethra). If detected early enough, prostate cancer is highly treatable, although, unfortunately, most men with early prostate cancer don't have any signs or symptoms. Symptoms usually indicate the the cancer has spread from the prostate gland to another part of the body, and the symptoms of advanced prostate cancer depend on where the cancer has spread to. According to Cancer Research UK, the most common place for prostate cancer to spread to is the bones, this can include the: Skull Spine Pelvis Ribs The most common symptom if cancer has spread to the bone is bone pain, and it is usually there most of the time and can wake you up at night, explains the charity. The pain can be a dull ache or stabbing pain, and you...

Prostate cancer grows in a very slow manner. This means those who suffer from it may not notice any symptoms at their early stages. The symptoms of prostate cancer oftentimes manifest only when the growth is already big. At this time, it starts to apply pressure on the tube called urethra. The urethra facilitates the ejection of urine from the bladder to the penis. You must be able to identify the symptoms because, like other forms of cancer, there is no cure for prostate cancer at present. Since the prostate gland is very near the urethra, many of the prostate cancer symptoms will start affecting how a person urinates. Macmillan Cancer Support, a specialist health care charity organization, there are two symptoms to watch out for. This would include difficulty in peeing and needing to urinate more often than necessary, particularly at night. signs of prostate cancer found in the urine Photo: edusoft - Pixabay Another symptom is having the feeling like you have not full...

Prostate cancer symptoms usually appear when the cancer has grown as it begins to put pressure on the tube that carries urine from the bladder out of the penis, known as the urethra. The cancer usually develops slowly, so may not show signs for many years. But it’s important to recognise symptoms when they do start to show because there’s currently no cure for cancer. But it’s also important to recognise that these symptoms can be caused by another condition called benign prostatic hyperplasia (BPH), or benign prostate enlargement (BPE). The NHS explains: “BPE is the medical term to describe an enlarged prostate, a condition that can affect how you pass urine. “BPE is common in men aged over 50. It's not a cancer and it's not usually a serious threat to health. “Many men worry that having an enlarged prostate means they have an increased risk of developing prostate cancer. This is not the case. DON'T MISS “The risk of prostate cancer is no greater for men with ...

The prostate is a small gland shaped like a walnut. Cancer growth in the area is called prostate cancer and primarily affects men as they advance in age. Oftentimes, prostate cancer symptoms do not manifest until it is large enough to put some pressure on the tube carrying urine from the bladder to the urethra or penis. At this stage, patients may experience some changes in their bladder and how they pee. Changes in Bladder Habits According to Macmillan Cancer Support, one of the biggest charitable organization and health care provider in the UK, those suffering from prostate cancer may have these symptoms:        Experience some difficulty in peeing, like, for instance, having a weak flow or the need to strain to begin urinating.        There is a need to urinate more often than normal, particularly during nighttime.        Feeling like the bladder was not completely emptied after urinating...

GLASGOW — Men who carry the BRCA2 gene mutation, which is linked to breast and ovarian cancer , are at risk of developing aggressive prostate cancer and so should undergo regular prostate-specific antigen (PSA) testing, suggest findings from a major study. The IMPACT Study involved almost 3000 men from 20 countries who were recruited from families known to harbor carriers of mutations of the BRCA1 and BRCA2 genes and who underwent annual PSA testing and biopsy. The study was presented at the National Cancer Research Institute (NCRI) 2019 Cancer Conference. The results, which were published recently  in European Urology,  show that men who carried the BRCA2 mutations were almost twice as likely to develop prostate cancer than were noncarriers. They were also diagnosed with prostate cancer at a younger age and had more clinically significant disease. "Our research shows very clearly that men with the BRCA2 gene fault are at increased risk of aggressive prostate cancer...

Prostate cancer is cancer that occurs in the prostate — a small walnut-shaped gland in men, and it mainly affects men as they get older. Prostate cancer does not usually cause any symptoms until the cancer has grown large enough to put pressure on the tube that carries urine from the bladder out of the penis (urethra). When this happens, people may experience a number of changes related to their bladder. Related articles According to Macmillan UK, people may experience the following changes to their bladder habits: Difficulty peeing – for example, a weak flow or having to strain to start peeing Needing to pee more often than usual, especially at night Feeling like you have not completely emptied your bladder after peeing An urgent need to pee Blood in the pee or semen Rarely, pain when peeing or ejaculating. As the NHS explains, these symptoms do not always mean you have prostate cancer, as many men's prostates get larger as they get older because of a non-canc...

In order to turn your prostate cancer into a couch potato and keep it from spreading, your best chance is not to be one yourself. Your prostate doesn’t care so much about the size of your muscles – it turns out that how “ripped” or “shredded” you are is not nearly as important as your cardiovascular health. Why should your prostate be so interested in your heart? What’s the connection? Here it is: Cardiovascular exercise can lower your risk of getting lethal prostate cancer and of having cancer come back if it’s already been treated. What the Latest Science Tells Us About Prostate Cancer June M. Chan, Sc.D., a Prostate Cancer Foundation (PCF)-funded epidemiologist and world-renowned expert on lifestyle and cancer, heads a research program at the University of California San Francisco that aims to uncover fixable risk factors for prostate cancer progression – elements of your lifestyle that you can change to lower your odds of dying from prostate cancer. In previous work, Chan and co...

At 70 years old, the retired engineer is fitter, stronger and has more energy than many of the 20-something students who workout alongside him. His high-intensity workout which involves running, cycling, rowing and lifting heavy weights is perhaps all the more impressive when you learn that Robert has been battling advanced prostate cancer for the last four-and-a-half years. Since his diagnosis in 2015, Robert has undergone gruelling sessions of radiotherapy, doses of hormone therapy and most recently chemotherapy. Although radiotherapy seemed to work initially, the disease subsequently spread to his lymph nodes and he developed a 14mm tumour in his chest. The toxic side effects of the treatments he was having made him put on weight and he felt sluggish and depressed. Then 18 months ago, Robert became the first man in the UK to take part in a pioneering multinational clinical trial looking at whether high-intensity exercise could extend the lives of men with metastatic prosta...

Men with a genetically high risk of developing prostate cancer should be given extra checks every year after they turn 40, scientists say.     One in four men who carry a fault in their DNA - a mutation on the BRCA2 gene - will develop the killer disease at some point in their life. Around one in 300 men in the UK have the mutation, which is similar to the BRCA-1 gene fault carried by Angelina Jolie . But most will not know because it is not routinely tested for.  Researchers now say if all of those men could be identified, they should be given an annual blood test to detect tumours early. In a study, men with the BRCA2 gene fault who had a blood test were diagnosed at a younger age – an average of 61 years, compared with 64. Men with a genetic risk of developing prostate cancer should be given extra checks every year after they turn 40, scientists at the Institute of Cancer Research say Experts at the Institute of Cancer Research (ICR), L...