Prostate Cancer

DOH helps clear the way for Alpha DaRT trials in our state A new cancer treatment shows an outstanding ability to shrink or eliminate tumors. In fact, the treatment shows such promise that the federal Food and Drug Administration (FDA) is granting it "breakthrough device status." This means that clinical trials — scientific studies with patients on safety and effectiveness — can move forward quickly. And Washington is one of the first states to authorize its use in those studies. Our role at DOH is to make sure patients are safe. Here's the story of how it came together. The science behind the discovery Alpha Tau Medical, a company in Israel, developed a new way to treat a certain type of tumor called a hard tumor. Breast cancer, bone cancer, lung cancer and prostate cancer are types of cancer ("solid cancers") that involve hard tumors. The treatment is called "Alpha DaRT" (Diffusing Alpha-Emitters Radioactive Therapy). It involves inserting a metal ...

By examining the long-term outcomes of males with negative transrectal ultrasound ( TRUS) biopsy results who did not get  MRI, 1 can investigate the oncologic risk of such malignancies. The goal was to analyze mortality following the first and second negative TRUS biopsies. All men who had initial TRUS biopsies were included between January 1, 1995, and December 31, 2016. A total of 6,389 men underwent a re-biopsy, and 37,214 men had a negative result from the initial TRUS biopsy. With competing risks, the risk of cause-specific death was examined. Prostate-specific antigen (PSA), age, and digital rectal examination were all considered in a multivariable logistic regression analysis of the diagnosis of Gleason grade more than equal to 7 prostate cancer after negative biopsies. Prostate cancer-specific mortality over 15 years was 1.9%  (95% [CI]: 1.7-2.1). For males with PSA levels of less than 10 and more than 20 ng/ml, respectively, the prostate cancer-specific deat...

Share on Pinterest Experts say changes in eating habits as people enter adulthood can cause weight gain. Raimund Koch/Getty Images Researchers report that the biggest weight gain in U.S. adults is happening in the mid-20s to mid-30s. They say people in that age group tend to shift focus from physical fitness to other issues such as jobs, families, and finances. Researchers also note that women tend to gain more weight during this time, in part because of weight gain during pregnancy. Experts say people of all ages should eat a more healthy diet and be patient if they are trying to lose weight. Step aside, "Freshman Fifteen," there's a new age-related weight gain in town. Call it the "Trend up Twenties" or perhaps the "Thickening Thirties," but researchers have found that the highest weight gain comes not in college or middle age, but in the early adult years. A new study, published in t he Journal of Obesity , is the first to hone in on how weight gain...

KUALA LUMPUR, July 2 – If you are a man with urination problems, such as frequently needing to pass urine especially disturbing your night sleep or trouble starting to pee, you should consider getting checked to see if you have benign prostatic hyperplasia (BPH). BPH is a condition in which a man has an enlarged prostate that may affect how he urinates. It doesn't usually pose serious harm to one's health, according to NHS UK, 1 but while symptoms may be mild for some without necessitating treatment, BPH can be very troublesome for other men. BPH, which primarily occurs among older men aged above 50, is not a cancer and does not lead to higher risk of developing prostate cancer, although symptoms can be similar. According to the National Health and Morbidity Survey (NHMS) 2019 2 about 16.3 per cent of adults in Malaysia aged 40 and above have probable BPH with moderate to severe symptoms – lower than the 26.2 per cent estimated lifetime global prevalence rate. Malaysi...

Prostate cancer is the most common form of cancer other than skin cancer in people who have a prostate (an organ that secretes fluid to protect and nourish sperm).  Depending upon the stage of the cancer, different treatment options are available. These treatment options include: This article will review how surgery and radiation are used to treat prostate cancer.  Both can be very effective forms of treatment in men with the disease.  Although they may have the same goals of therapy, there are differences between these treatments.  Be sure to see your healthcare provider for the diagnosis, so you can receive the best treatment for you. The Good Brigade / Getty Images What to Know About Surgery Surgical treatment for prostate cancer may be considered when the cancer has not spread outside the prostate. How Does It Work?  There are multiple types of surgery that can be used. Rad...

Abstract Aim This study uses OCT imaging to examine morphological changes at the chorioretinal interface of the choroidal melanoma biopsy site over time. Setting Liverpool Ocular Oncology Centre (LOOC), St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom. Methodology Retrospective analysis of all patients who underwent 25G vitrector-assisted transretinal biopsy for choroidal melanoma between 1st Jan 2017 and 31st Dec 2019. The biopsy procedure does not involve full vitrectomy, treatment of the retinal hole or tamponade. Patients routinely undergo OCT imaging over the tumour site at each follow up. Cases required a minimum of a baseline OCT and two consecutive post-operative OCT scans of adequate quality, overlying the biopsy site. All images were reviewed and graded by an ophthalmic specialist. Results Fifty-one patients met the criteria for inclusion. OCT analysis identified 2 characteristic morphologies following transretinal biopsy –a choroidal pl...

Background Malignant bone tumor involving the pelvis accounts for 5–10%. 1,2 External hemipelvectomy (hindquarter amputation) is used as the mainstay surgery for unremoved tumors of the pelvis. 3 With the advances in imaging, chemotherapy, radiation therapy, and surgical techniques have allowed more patients to be managed with limb-sparing surgery. An internal hemipelvectomy technique was introduced to remove the tumor with limb preservation in these particular patients. 4 Many alternative bone reconstructions following internal hemipelvectomy have been reported by using non-vascularized autograft, free-vascularized autograft, allograft, recycling bone (autoclaved, pasteurized, and extracorporeal radiation), allograft-prosthetic composite (APC), saddle prosthesis, custom prosthesis, arthrodesis and no bone reconstruction. 5–17 Complications following internal hemipelvectomy with or without bone reconstruction are reported at around 50–80%. Most complications are related to woun...