Prostate cancer patients aren't getting testosterone suppression injections on time - The Cancer Letter

-

publication date: Jul. 24, 2020

46-30-late-web

Real-World Evidence

Payment policies blamed for non-compliance with treatment guidelines

By Matthew Bin Han Ong

The vast majority of patients with prostate cancer in the United States don’t receive androgen deprivation therapy injections on time. Up to 84% of injections are delayed for patients on a 28-day schedule, according to an authoritative study published in the The Journal of Urology.

The study, conducted by researchers from more than a dozen institutions, used real-world claims data from 22,860 patients with prostate cancer who were treated with luteinizing hormone-releasing agonists and who had one measurement of PSA or testosterone. The retrospective analysis included data from January 2007 through June 2016.

Delays in hormone therapy should be avoided to prevent adverse outcomes, prostate cancer experts say. Multiple studies have established a relationship between maintaining testosterone at castration levels and lowered risk of progression of prostate cancer. These delays are primarily caused by reimbursement policies that don’t adhere to clinical guidelines and FDA labeling, experts say.

“LHRH therapy is the mainstay of advanced prostate cancer therapy. It’s the foundation for all additional therapies,” Jason M. Hafron, one of the study authors, and director of research at the Michigan Institute of Urology, said to The Cancer Letter. “So, it’s critical that we adhere to the timeliness or the appropriate dosing of these drugs. I really don’t want to point the finger at physicians, because it’s not just the physicians, it’s the whole system that is essentially flawed.”

A conversation with Hafron, who is also associate professor of urology at the William Beaumont School of Medicine … Continue reading Prostate cancer patients aren’t getting testosterone suppression injections on time

To access this members-only content, please log in.
Institutional subscribers, please log in with your IP.
If you're not a subscriber why not join today?
To gain access to the members only content click here to subscribe.
You will be given immediate access to premium content on the site.
Click here to join.


Comments

Post a Comment

Popular posts from this blog

I Wish I Didn't Need an Oncologist at All, But I'm Thankful for the One ...

-
Image
efudex side effects :: Article Creator Inmates Given Ivermectin In Jail Will Each Get $2,000 After Settlement Your browser is not supporteddetroitnews.Com detroitnews.Com wants to ensure the best experience for all of our readers, so we built our site to take advantage of the latest technology, making it faster and easier to use. Unfortunately, your browser is not supported. Please download one of these browsers for the best experience on detroitnews.Com Efudex Cream Efudex Cream Generic Name & Formulations General Description Fluorouracil 5%. Pharmacological Class Antimetabolite. How Supplied Soln (w. Drop dispenser)—10mL, 25mL; Crm—40g Efudex Cream Indications Indications Multiple actinic or solar keratoses. Superficial basal cell carcinoma when conventional therapy is impractical (5% only); see full labeling. Efudex Cream Dosage and Administration Adult Keratoses: Apply twice daily until eros
Read more

Early symptoms of cancer in males: Common warning signs

-
Image
fluciclovine f 18 :: Article Creator The U.S. Navy Might Be Done With The F/A-18 Super Hornet Fighter Will The U.S. Navy Receive Its Final F/A-18 Super Hornets? - Around the holidays, money can be tight, a fact that the United States Navy has also learned as its negotiations to buy the last batch of Super Hornets are reportedly stalled over the growing price tag. USNI News reported on Tuesday that the contract for the U.S. Navy to purchase the final twenty F/A-18 E/F Super Hornets from aerospace giant Boeing appears to be at a standstill. The Navy continues to work with Boeing on the contract for the 20 congressionally added Super Hornet aircraft. Ongoing contract negotiations cannot be discussed at this time," Capt. Michael Burks, the program manager for the F/A-18 and EA-18G office at Naval Air Systems Command, told USNI News in a statement. Previous estimates put the unit cost of the final batch of aircraft at $55.7 million, and la
Read more

20 Famous Men Who Have Had Prostate Cancer

-
Image
leukemia treatment options :: Article Creator Current And Breakthrough Treatments For Chronic Lymphocytic Leukemia (CLL) Chronic lymphocytic leukemia (CLL) is a slow-growing cancer of the immune system. Because it's slow-growing, many people with CLL won't need to start treatment for many years after their diagnosis. Once the cancer begins to grow, there are many available treatment options that can help people achieve remission. This means people can experience long periods of time when there's no sign of cancer in their bodies. The exact treatment option that you'll receive depends on a variety of factors. This includes: whether your CLL is symptomatic the stage of the CLL, based on results of blood tests and a physical exam your age your overall health While there's no cure for CLL yet, breakthroughs in the field are on the horizon. Doctors typically stage CLL using a system called the Rai system. Low
Read more