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Exosomal ncRNAs in liquid biopsy: a new paradigm for early cancer diagnosis and monitoring

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- October 19, 2025

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Cancer Glossary | Definitions & Phonetic Pronunciations

- May 04, 2025

mucositis treatment :: Article Creator Vitamins By Condition Learn about User Reviews and read IMPORTANT information about user generated content Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source i...

Sentinel lymph node biopsy: What cancer patients should know

- May 07, 2024

cancer lump on neck :: Article Creator Doctor Watching TV Show Spotted Cancer On Show's Guest That She Didn't Know About Say what you will about social media and daytime TV, but sometimes, they can help work wonders. In fact, the power of Facebook and the popularity of HGTV's Beachfront Bargain Hunt played a big part in helping Nicole McGuiness get ahead of her serious cancer diagnosis - but it was an eagle-eyed doctor who really saved her bacon. The then-32-year-old appeared on the property series alongside her father while in search of a holiday home in North Carolina to celebrate her recent recovery from brain cancer in May 2018. She explained that she had set her sights on 'something near the water', specifically a beachfront property in Morehead City, to start afresh in this new phase of her life. Dr. Erich Voigt was one of the viewers who tuned into the Beachfront Bargain Hunt episode, which Nicole featured in, an...

Expert Discusses Data From First Positive Trial for PARP Inhibitor in Prostate Cancer - Targeted Oncology

- November 05, 2019

Alan Bryce, MD PARP inhibition with olaparib (Lynparza) improved radiographic progression-free survival (rPFS) in heavily pretreated patients with metastatic castration-resistant prostate cancer (mCRPC) who had alterations in homologous recombination repair (HRR) genes, according to findings from the phase III PROfound trial presented at the 2019 ESMO Congress. This was the first positive randomized phase III trial reported evaluating a PARP inhibitor in men with mCRPC. The PROfound trial enrolled patients to 2 cohorts. In cohort A, 245 patients with BRCA1/2 or ATM alterations, markers of HRR, were randomized 2:1 to receive either olaparib (n = 162) or physician’s choice of abiraterone acetate (Zytiga) with prednisone or enzalutamide (Xtandi) (n = 83). In cohort B, 142 patients with alterations in the BARD1, BRIP1, CDK12, CHEK1/2, FANCL, PALB2, PPP2R2A, RAD51B/C/D , or RAD54L , all of which are associated with HRR indirectly, were also randomized 2:...

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Expert Discusses Data From First Positive Trial for PARP Inhibitor in Prostate Cancer - Targeted Oncology

- November 05, 2019

Alan Bryce, MD PARP inhibition with olaparib (Lynparza) improved radiographic progression-free survival (rPFS) in heavily pretreated patients with metastatic castration-resistant prostate cancer (mCRPC) who had alterations in homologous recombination repair (HRR) genes, according to findings from the phase III PROfound trial presented at the 2019 ESMO Congress. This was the first positive randomized phase III trial reported evaluating a PARP inhibitor in men with mCRPC. The PROfound trial enrolled patients to 2 cohorts. In cohort A, 245 patients with BRCA1/2 or ATM alterations, markers of HRR, were randomized 2:1 to receive either olaparib (n = 162) or physician’s choice of abiraterone acetate (Zytiga) with prednisone or enzalutamide (Xtandi) (n = 83). In cohort B, 142 patients with alterations in the BARD1, BRIP1, CDK12, CHEK1/2, FANCL, PALB2, PPP2R2A, RAD51B/C/D , or RAD54L , all of which are associated with HRR indirectly, were also randomized 2:...

Sentinel lymph node biopsy: What cancer patients should know

- May 07, 2024

cancer lump on neck :: Article Creator Doctor Watching TV Show Spotted Cancer On Show's Guest That She Didn't Know About Say what you will about social media and daytime TV, but sometimes, they can help work wonders. In fact, the power of Facebook and the popularity of HGTV's Beachfront Bargain Hunt played a big part in helping Nicole McGuiness get ahead of her serious cancer diagnosis - but it was an eagle-eyed doctor who really saved her bacon. The then-32-year-old appeared on the property series alongside her father while in search of a holiday home in North Carolina to celebrate her recent recovery from brain cancer in May 2018. She explained that she had set her sights on 'something near the water', specifically a beachfront property in Morehead City, to start afresh in this new phase of her life. Dr. Erich Voigt was one of the viewers who tuned into the Beachfront Bargain Hunt episode, which Nicole featured in, an...

Prostate MRI in Stereotactic Body Radiation Treatment Planning and Delivery for Localized Prostate Cancer - RSNA Publications Online

- June 20, 2022

Abstract In patients with prostate cancer, prostate MRI can be used to detect and diagnose disease, identify dominant intraprostatic lesions that may be treated with a higher radiation dose, help segment radiation treatment targets, and evaluate fiducial marker and hydrogel spacer placements for radiation treatment planning and delivery. Prostate MRI is increasingly being used to make diagnoses and guide management for patients receiving definitive radiation treatment for prostate cancer. Radiologists should be familiar with the potential uses of prostate MRI in radiation therapy planning and delivery. Radiation therapy is an established option for the definitive treatment of localized prostate cancer. Stereotactic body radiation therapy (SBRT) is an external-beam radiation therapy method used to deliver a high dose of radiation to an extracranial target in the body, often in five or fewer fractions. SBRT is increasingly being used for prostate cancer treatment and has been recognized ...

What are the top 5 warning signs of prostate cancer?

- November 03, 2024

hcc treatment :: Article Creator TARE In Advanced HCC: When Is It Optimal And Why? Jin Woo Choi, MD, PhDSeoul National University Hospital Seoul National UniversitySeoul, Republic of Koreajwchoi.Med@snu.Ac.KrDisclosures: None. Transarterial radioembolization (TARE) can be considered for patients with unilobar hepatocellular carcinoma (HCC) and ipsilateral portal vein tumor thrombosis (Vp1-3), provided there is no hepatic vein invasion, no extrahepatic spread, Child-Pugh A status, and an ECOG (Eastern Cooperative Oncology Group) performance status of 0 to 1. Although this represents an advanced stage of HCC, locoregional treatments may still be viable, and an effective locoregional treatment can potentially increase the likelihood of curative outcomes. Despite the rapid development of immune checkpoint inhibitors, which are now the frontline treatment for advanced HCC, there is a significant lack of detailed data for this specific patient popul...

Cancer Glossary | Definitions & Phonetic Pronunciations

- February 04, 2026

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7 pain management options for cancer patients you might not know about

- November 12, 2024

systemic radiation therapy :: Article Creator The Four Types Of Systemic Therapy For Breast Cancer Just a moment... This request seems a bit unusual, so we need to confirm that you're human. Please press and hold the button until it turns completely green. Thank you for your cooperation! Press and Hold Press and hold the button If you believe this is an error, please contact our support team. 167.71.87.121 : 812cda26-e6e3-4c13-af8c-696bf35e Revolutionizing Prostate Cancer Treatment: The Promise Of Stereotactic Radiotherapy Prostate cancer stands as Australia's most frequently diagnosed cancer, with one in six men confronting a diagnosis by age 85. As cells grow uncontrollably, cancers may invade nearby tissues or spread, a progression referred to as metastases. While early-stage treatment typically involves localized surgery or radiation, advanced cancer requires systemic therapies like chemotherapy. A new form of...

The underexplored links between cancer and the internal body climate: Implications for cancer prevention and treatment

- March 20, 2025

cervical cancer discharge :: Article Creator I Was Diagnosed With Cervical Cancer At 38 – This Is Why You Should Never Miss A Smear Test Lauren Jolly runs a busy life between her job as the head of buying for a women's wear retailer and her role at home as a wife to Matt and mother of Jack, seven, and Rhys, five. In 2023, Towcester-based Lauren's life slowed down significantly when the then 38-year-old was diagnosed with cervical cancer. "We walked into the room, and my doctor introduced us to a Macmillan nurse, so I instantly knew it was about to be bad news," Lauren remembers. "In the space of a week, I had a PET scan, an MRI scan, and then a CT scan." Lauren discovers symptoms Lauren had always been someone who was on top of her smear tests. "I grew up during the era of Jade Goody, so there was probably more awareness in my age group because she was a huge celebrity who died of cervical cancer," she e...

Tumor biomarkers for diagnosis, prognosis and targeted therapy | Signal Transduction and Targeted Therapy

- February 05, 2026

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'Bold' Prostate Cancer Trial Enrolls 'Very, Very Quickly' - Medscape

- April 29, 2020

Once the stuff of headlines and clinical buzz, sipuleucel-T ( Provenge , Dendreon) has had a steep decline in its profile as a prostate cancer treatment. But the stage is being set for a possible comeback. To much fanfare in 2010, the drug became the first-ever immunotherapy for metastatic prostate cancer to be approved by the US Food and Drug Administration, albeit in a protracted and controversial process. In the final data set, it improved overall survival by 4 months compared with placebo. It is an unusual product. Sometimes referred to as a vaccine and usually called by its trade name, Provenge is an autologous active cellular immunotherapy, made individually for each patient. Clinical uptake of the product was slow, and, after launch, it soon faced stiff competition from other new drugs for advanced disease. Ten years after approval, the once-hyped therapy is now seldom mentioned, and, according to the company, has only 8% penetration of the metastatic prostate cancer ma...