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Efudex Cream
Efudex Cream Generic Name & Formulations General DescriptionFluorouracil 5%.
Pharmacological ClassAntimetabolite.
How SuppliedSoln (w. Drop dispenser)—10mL, 25mL; Crm—40g
Efudex Cream Indications IndicationsMultiple actinic or solar keratoses. Superficial basal cell carcinoma when conventional therapy is impractical (5% only); see full labeling.
Efudex Cream Dosage and Administration AdultKeratoses: Apply twice daily until erosion occurs (usually 2–4 wks). Basal cell carcinoma (5% only): Apply twice daily, usually for 3–6 weeks (obliteration may take 10–12 weeks).
ChildrenNot established.
Efudex Cream Contraindications ContraindicationsDihydropyrimidine dehydrogenase (DPD) deficiency. Pregnancy.
Efudex Cream Boxed WarningsNot Applicable
Efudex Cream Warnings/Precautions Warnings/PrecautionsDo not apply into eyes, nose, or mouth. Avoid mucous membranes, occlusion, ulcerated/inflamed skin, exposure to UV light. Wash hands after application if fingers were used. Advise patients of expected skin reaction. Biopsy unresponsive lesions. Nursing mothers: not recommended.
Efudex Cream PharmacokineticsSee Literature
Efudex Cream InteractionsNot Applicable
Efudex Cream Adverse Reactions Adverse ReactionsBurning, crusting, allergic contact dermatitis, pruritus, scarring, rash, soreness, ulceration; leukocytosis.
Efudex Cream Clinical TrialsSee Literature
Efudex Cream NoteNot Applicable
Efudex Cream Patient CounselingSee Literature
Efudex Cream Generic Name & Formulations General DescriptionFluorouracil 5%.
Pharmacological ClassAntimetabolite.
How SuppliedSoln (w. Drop dispenser)—10mL, 25mL; Crm—40g
Efudex Cream Indications IndicationsMultiple actinic or solar keratoses. Superficial basal cell carcinoma when conventional therapy is impractical (5% only); see full labeling.
Efudex Cream Dosage and Administration AdultKeratoses: Apply twice daily until erosion occurs (usually 2–4 wks). Basal cell carcinoma (5% only): Apply twice daily, usually for 3–6 weeks (obliteration may take 10–12 weeks).
ChildrenNot established.
Efudex Cream Contraindications ContraindicationsDihydropyrimidine dehydrogenase (DPD) deficiency. Pregnancy.
Efudex Cream Boxed WarningsNot Applicable
Efudex Cream Warnings/Precautions Warnings/PrecautionsDo not apply into eyes, nose, or mouth. Avoid mucous membranes, occlusion, ulcerated/inflamed skin, exposure to UV light. Wash hands after application if fingers were used. Advise patients of expected skin reaction. Biopsy unresponsive lesions. Nursing mothers: not recommended.
Efudex Cream PharmacokineticsSee Literature
Efudex Cream InteractionsNot Applicable
Efudex Cream Adverse Reactions Adverse ReactionsBurning, crusting, allergic contact dermatitis, pruritus, scarring, rash, soreness, ulceration; leukocytosis.
Efudex Cream Clinical TrialsSee Literature
Efudex Cream NoteNot Applicable
Efudex Cream Patient CounselingSee Literature
New Side Effects From Ozempic Are Emerging As More Take The Drug. Experts Explain How To Manage Them
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