Bladder cancer - Symptoms and causes
Hyperthermia: How It Treats Cancer, Uses High Temperatures, And More - WebMD
Hyperthermia is the process of increasing your body temperature to a higher level than normal. Typically, a high body temperature is characterized by a fever. It can be associated with heatstroke too. However, hyperthermia is also a treatment that uses heat to kill cancer cells as well as for other medical purposes. When hyperthermia is used to treat cancer it is also called thermal therapy, thermal ablation, or thermotherapy.
Your doctor will use hyperthermia treatment to target certain cancers. This treatment increases the body temperature and changes your cell structures.
Hyperthermia is used to make other cancer treatments like radiation therapy or chemotherapy more effective. In some cases, the extreme heat can kill cancer cells altogether. But this also kills or harms normal cells and tissue.
Also known as heat therapy. Hyperthermia is used as a cancer treatment because the heat is supposed to shrink tumors. The heat keeps those cells from getting what they need to live. Hyperthermia is not a regularly used cancer treatment. It's often used as a supplement to other treatments. Most cases of this treatment are still used in research settings.
Hyperthermia has been used for over 30 years. While it's not a standard treatment for cancer, its therapeutic and targeted properties have been used for a long time. It is a safe and effective therapy for cancer.
There are three types of hyperthermia treatment for cancer.
Local hyperthermia. This type of treatment focuses on a single tumor or other small areas. The heat is applied from the outside, aimed at the tumor. It can also be heated on the inside of your body. This is done with a thin, heated wire probe.
Different types of energy that might be used include microwave, radiofrequency, and ultrasound. How your doctor approaches local hyperthermia will depend on where your tumor is.
Regional hyperthermia. This is used when targeting an organ or limb. Your doctor will use a device that produces a lot of heat. It's then placed over the region you're targeting. In a process called profusion, your blood may be removed, heated, then pumped into the target region.
The profusion technique is typically reserved for cancers like melanoma or cancer in your liver or lungs. The heated blood is pumped back to your organ or limb. This treatment is usually accompanied by anticancer drugs. This is an internal targeting technique.
Whole-body hyperthermia. This treatment targets your whole body. Your doctor may use warm water blankets. You could also be placed in a thermal room or chamber. Your whole body will be heated and targeted to treat your cancer.
Your doctor may suggest hyperthermia treatment in cases where cancer has recurred. If your body won't be able to handle a second full course of radiation therapy, you may get hyperthermia treatment. Pairing the two therapies can kill your cancer cells.
There are many benefits to using heat therapy. Hyperthermia treatment is great for treating cancers that have already been treated with radiation.
Hyperthermia is good for small tumors that can be targeted locally. This treatment is also good if you have cervical, head, and neck cancer. It's also good for melanoma or other locally advanced cancers.
Hyperthermia treatment's benefit is that it can target your body with an exact temperature. It also has a very accurate target. Doctors use hyperthermia as a part of the cancer treatment strategy and not as the entire strategy.
Another benefit of hyperthermia treatment is how your body responds to the treatment. There's an improved immune response when you undergo this treatment. Your body activates cells that boost your immunotherapy. There are still clinical trials uncovering the effects of hyperthermia and immunotherapy.
Like other cancer treatments and therapies, there are side effects to hyperthermia. Side effects can differ based on the type of hyperthermia treatment you received.
Local hyperthermia side effects. Include pain at the site of therapy. You could also have:
Regional and whole-body hyperthermia side effects. These side effects will depend on where and how hot your treatment was. You may experience:
Other serious but rare side effects of regional and whole-body hyperthermia treatment include:
You can talk to your doctor about the right treatment for you. If your cancer has recurred, hyperthermia might be an option to supplement other cancer therapies you're participating in.
Sona Announces Ethics Committee Approval For Melanoma Clinical Trial
Halifax, Nova Scotia--(Newsfile Corp. - June 27, 2025) - Sona Nanotech Inc. (CSE: SONA) (OTCQB: SNANF) (the "Company", "Sona"), an oncology-focused life sciences company developing innovative therapies based on its uniquely biocompatible gold nanorod technology, announces that it has received ethics committee approval to proceed with its previously announced early feasibility study of its Targeted Hyperthermia Therapy ("THT") cancer treatment.
Sona CEO David Regan commented, "This ethics committee approval gives us the green light we've been waiting for to begin enrolling patients suffering from late-stage melanoma, for whom no other therapy has worked, to participate in our first-in-human clinical trial. Our clinical trial partner will now begin enrolling patients, and we will advise when a first dosing of our THT treatment has occurred. Sona's CMO, Dr. Carman Giacomantonio, will provide clinical training and will observe the application of THT in the first patients enrolled."
The study is designed to assess safety, tolerability, and preliminary efficacy and will include two treatments of Sona's THT, one week apart, for patients with advanced melanoma who are on, but have failed to respond to, a standard of care immunotherapy protocol. The study is anticipated to be conducted this summer with an initial read-out of final results expected by September, subject to enrollment rates.
Contact:David Regan, CEO+1-902-442-0653david@sonanano.Com
About Sona Nanotech Inc.Sona Nanotech is developing Targeted Hyperthermia™, a photothermal cancer therapy, which uses therapeutic heat to treat solid cancer tumors. The heat is delivered to tumors by infrared light that is absorbed by Sona's gold nanorods in the tumor and re-emitted as heat. Therapeutic heat (42-48°C) stimulates the immune system, shrinks tumors, inactivates cancer stem cells, and increases tumor perfusion – thus enabling drugs to reach all tumor compartments more effectively. Targeted Hyperthermia promises to be safe, effective, minimally invasive, competitive in cost, and a valuable adjunct to drug therapy and other cancer treatments.
Sona has developed multiple proprietary methods for the manufacture of gold nanoparticles which it uses for the development of both cancer therapies and diagnostic testing platforms. Sona Nanotech's gold nanorod particles are cetyltrimethylammonium ("CTAB") free, eliminating the toxicity risks associated with the use of other gold nanorod technologies in medical applications.
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CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING INFORMATION: This press release includes certain "forward-looking statements" under applicable Canadian securities legislation, including statements regarding the anticipated applications and potential opportunities of Targeted Hyperthermia Therapy, and Sona's preclinical and clinical study plans. Forward-looking statements are necessarily based upon a number of assumptions or estimates that, while considered reasonable, are subject to known and unknown risks, uncertainties, and other factors which may cause the actual results and future events to differ materially from those expressed or implied by such forward-looking statements, including the risk that Sona may not be able to successfully obtain sufficient clinical and other data to submit regulatory submissions, raise sufficient additional capital, secure patents or develop the envisioned therapy, and the risk that THT may not prove to have the benefits currently anticipated. There can be no assurance that such statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking statements. Sona disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.
Not for distribution to United States newswire services or for dissemination in the United States
To view the source version of this press release, please visit https://www.Newsfilecorp.Com/release/257072
Hyperthermia Therapy Revolutionizes Cancer Treatment
This therapy can also improve the efficacy of other treatments such as radiation and chemotherapy, and it can offer relief from pain and inflammation in specific instances.
Por Editorialsdr el February 26, 2025
Hyperthermia therapy is a medical treatment that utilizes heat to treat a variety of conditions, particularly cancer. It entails increasing the body's temperature or focusing on a specific area of the body to harm or eliminate cancer cells. This therapy can also improve the efficacy of other treatments such as radiation and chemotherapy, and it can offer relief from pain and inflammation in specific instances.
Research suggests that heating cells up to 113°F can effectively promote cancer cell death and damage proteins and other structures within cancer cells. This can help shrink tumors and prevent the spread of cancer cells. This therapy is used to treat metastatic cancer that has spread throughout the body, achieved by raising the body temperature to 104° F.
How Hyperthermia Therapy WorksHyperthermia works exploiting the thermal sensitivity of tumor cells. These cells are more prone to heat than normal cells because they have a decreased ability to dissipate heat, which ultimately results in the destruction of cancer cells. Tumors are also susceptible to thermal damage when combined with radiotherapy or chemotherapy.
Direct destruction of tumor cells occurs when the cell dies from heat, causing changes in the membranes and resulting in the rupture of cancer cells.
The efficacy of radiotherapy and chemotherapy is improved by the heat mechanisms that penetrate cells and interfere with DNA repair in tumor cells, making them more sensitive to radiation or drugs. Additionally, increased blood flow allows for greater effectiveness of the drugs administered.
Immunomodulation: Heat reactivates the immune system by aiding the body in recognizing and attacking tumor cells.
Heat can be applied in various ways, including:
Head and neck cancer: Hyperthermia helps improve local tumor control and reduce the side effects of radiation therapy.
Breast cancer: The combination of hyperthermia and radiotherapy increases the response rate and may improve survival in selected cases.
Skin cancer (melanoma): Hyperthermia enhances the effectiveness of radiotherapy in treating certain melanomas, particularly those in superficial areas of the skin.
Gynecological cancers (such as ovarian and cervical cancer): When combined with chemotherapy, hyperthermia has been shown to enhance the effectiveness of treatment for these types of cancer.
How Whole Body Hyperthermia is AdministeredTijuana, known as the world capital of alternative therapies, offers a variety of treatments, including hyperthermia therapy. Immunity Therapy Center (ITC) is one of the few facilities in the area that offers full-body hyperthermia.
Hyperthermia treatment can be administered to the patient in various forms. Local hyperthermia focuses heat on a specific area of the body, while whole body hyperthermia heats the entire body. Whole body hyperthermia is typically used for metastatic cancer that has spread beyond the initial area. The goal of whole body hyperthermia is to raise the core body temperature to around 107-108°F in order to kill malignant cells. This is often achieved using hot water blankets or thermal chambers, which resemble large human-sized incubators. To ensure proper temperature regulation of both the tumor and surrounding tissue, the doctor may insert needles or probes with small thermometers in addition to the cancer therapy.
Whole-body hyperthermia is an excellent alternative method for treating patients with metastatic cancer. It targets malignant cells directly in the body, making it an efficient therapy for most types of cancer. Many cancer patients find hyperthermia treatment to be a beneficial alternative to conventional treatments because of its non-invasive qualities.
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